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Atevirdine mesylate

NNRT Inhibitor

Atevirdine mesylate is a nonnucleoside reverse transcriptase (NNRT) inhibitor effective against human immunodeficiency virus type 1 (HIV-1), exhibiting an IC50 range of 0.06-1.6 μM. This compound demonstrates potent synergistic effects when combined with Zidovudine and Didanosine against resistant clinical isolates of HIV-1. Atevirdine mesylate is valuable for research in the field of AIDS and contributes to the understanding of antiviral therapies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	138540-32-6
Applications	NNRT Inhibitor
Formula	C₂₂H₂₉N₅O₅S
Molecular Weight	475.56
Synonyms	U 87201E mesylate
SMILES	CS(=O)(O)=O.CCNC1=C(N2CCN(C(C3=CC4=C(C=CC(OC)=C4)N3)=O)CC2)N=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.