Fig. 1 · Structure
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ATF4-IN-2
ATF4 Inhibitor
ATF4-IN-2 is a selective inhibitor of the Activating Transcription Factor 4 (ATF4) with an IC50 value of 47.71 nM. This compound is instrumental in investigating the role of ATF4 in various biological processes, particularly in the context of neurodegenerative diseases. Its application in research may aid in understanding the molecular mechanisms underlying these conditions and assist in the development of potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2991057-60-2 |
| Applications | ATF4 Inhibitor |
| Formula | C24H21BrClN5O4 |
| Molecular Weight | 558.81 |
| SMILES | O=C(C1=NN=C(C2=CC=C(Br)C=C2)O1)NCC3CCN(NC(C4=CC5=CC(Cl)=CC=C5O4)=O)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.