Fig. 1 · Structure
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ATPA
GluR5 Activator
ATPA is a selective activator of the glutamate receptor GluR5, exhibiting EC50 values of 0.66 μM for GluR5wt and varying affinities for multiple mutant forms, including 9.5 μM for GluR5(S741M) and 1.4 μM for GluR5(S721T). This compound is valuable for investigating the functional roles of GluR5 in synaptic transmission and plasticity. ATPA may also be utilized in research focused on neurological disorders where glutamate signaling is implicated.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 140158-50-5 |
| Applications | GluR5 Activator |
| Formula | C10H16N2O4 |
| Molecular Weight | 228.25 |
| SMILES | O=C(O)C(N)CC1=C(C(C)(C)C)ONC1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.