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Atriopeptin III (rat)

Catalog No.: A61967
Vasodilator
Atriopeptin III (rat), a 24-amino acid atrial peptide, serves as a potent vasodilator and natriuretic agent. This compound enhances renal function while effectively reducing blood pressure, particularly demonstrated in ureter-obstructed rat kidney models. Atriopeptin III (rat) is valuable for research related to chronic renal failure and its associated mechanisms.
Atriopeptin III (rat) 90817-13-3 Vasodilator
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAtriopeptin III (rat), a 24-amino acid atrial peptide, serves as a potent vasodilator and natriuretic agent. This compound enhances renal function while effectively reducing blood pressure, particularly demonstrated in ureter-obstructed rat kidney models. Atriopeptin III (rat) is valuable for research related to chronic renal failure and its associated mechanisms.
Product Information
Catalog NumA61967
FormulaC107H165N35O34S2
Molecular Weight2549.80
CAS Number90817-13-3
SequenceSer-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge:Cys3-Cys19)
Sequence shorteningSSCFGGRIDRIGAQSGLGCNSFRY (Disulfide bridge:Cys3-Cys19)
SMILES[C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(O)=O)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@@H](NC(=O)[C@@H]3CSSC[C@H](NC([C@@H](NC([C@H](CO)N)=O)CO)=O)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@]([C@H](CC)C)(C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N3)[H])[H])CC(N)=O)=O)CO)=O
SynonymsANP 127-150 (rat)
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GPCR/G Protein > Natriuretic Peptide Receptor (NPR)