Fig. 1 · Structure
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Atromentin
FabK Inhibitor
Atromentin is a selective FabK inhibitor that targets enoyl-ACP reductase, exhibiting an IC50 value of 0.24 μM. Isolated from the wood fungus Hypoxylon fendleri BCC32408, Atromentin shows significant selectivity over FabI. This compound is suitable for antimicrobial research, providing insights into the mechanisms of bacterial resistance and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 519-67-5 |
| Applications | FabK Inhibitor |
| Formula | C18H12O6 |
| Molecular Weight | 324.29 |
| SMILES | O=C1C(O)=C(C(=O)C(O)=C1C=2C=CC(O)=CC2)C=3C=CC(O)=CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.