ATV399 is an allosteric inhibitor of inducible nitric oxide synthase (iNOS) that effectively reduces nitric oxide (NO) production by preventing iNOS dimerization. This compound offers protective effects on rat pancreatic islet β-cells by mitigating cytokine-induced mitochondrial stress, endoplasmic reticulum stress, and apoptosis. ATV399 is suitable for research applications focused on type 1 diabetes and related metabolic disorders.
ATV399 is an allosteric inhibitor of inducible nitric oxide synthase (iNOS) that effectively reduces nitric oxide (NO) production by preventing iNOS dimerization. This compound offers protective effects on rat pancreatic islet β-cells by mitigating cytokine-induced mitochondrial stress, endoplasmic reticulum stress, and apoptosis. ATV399 is suitable for research applications focused on type 1 diabetes and related metabolic disorders.
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