Documents & Downloads

ATXN1-MED15 PPI-IN-1

ATXN1/MED15 Inhibitor

ATXN1-MED15 PPI-IN-1 is a potent inhibitor targeting the interaction between ATXN1 and MED15. It effectively binds to ATXN1 residues 99-163, disrupting both the ATXN1-MED15 association and the dimerization of polyQ-expanded ATXN1. This compound is valuable for research into Spinocerebellar Ataxia Type 1, providing insights into molecular mechanisms and potential therapeutic strategies.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	420106-23-6
Applications	ATXN1/MED15 Inhibitor
Formula	C₂₉H₂₁NO₄
Molecular Weight	447.48
SMILES	O=C(/C=C/C1=CC=C(NC(C2=C(C3=CC=CC=C3C(O)=O)C=CC=C2)=O)C=C1)C4=CC=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.