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AURKA-IN-4

AURKA Inhibitor

AURKA-IN-4 is a selective inhibitor of Aurora kinase A (AURKA), acting as a molecular glue within the AURKA/PHB2/LC3 complex. This compound specifically targets the mitochondrial pool of AURKA, effectively inhibiting AURKA-dependent mitophagy. AURKA-IN-4 is valuable for research related to cancer biology and mitochondrial dynamics, making it a crucial tool for studying AURKA's role in tumor progression and cellular homeostasis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	89575-11-1
Applications	AURKA Inhibitor
Formula	C₁₂H₁₇NO₃
Molecular Weight	223.27
SMILES	COC1=CC(CNC(CCC)=O)=CC=C1O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.