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Aurora A/PKC-IN-1

AurA/PKC Inhibitor

Aurora A/PKC-IN-1 is a potent dual inhibitor targeting Aurora A (AurA) and protein kinase C (PKC), specifically α, β1, β2, and θ isoforms, with IC50 values of 6.9 nM and 16.9 nM, respectively. This compound exhibits significant antiproliferative effects in breast cancer cells, as well as antimetastatic activity. It serves as a valuable research tool for studying cell proliferation mechanisms and therapeutic strategies in cancer biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3031505-76-4
Applications	AurA/PKC Inhibitor
Formula	C₁₆H₁₄N₆OSe₂
Molecular Weight	464.24
SMILES	O=C1N(C2=NC(N[C@@H]3C[Se]CC3)=C4N=CNC4=N2)[Se]C5=C1C=CC=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.