Fig. 1 · Structure
Documents & Downloads
AV-153
Antimutagenic
AV-153 is a 1,4-dihydropyridine (1,4-DHP) derivative that functions as an antimutagenic agent. It intercalates into DNA, facilitating the reduction of single-strand breaks and enhancing DNA repair mechanisms in human cells in vitro. By interacting with thymine and cytosine, AV-153 also influences poly(ADP)ribosylation. Additionally, this compound exhibits notable anti-cancer activities, making it valuable for research in cancer biology and DNA repair mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 27296-05-5 |
| Applications | Antimutagenic |
| Formula | C14H18NNaO6 |
| Molecular Weight | 319.29 |
| SMILES | O=C(C1=C(C)NC(C)=C(C(OCC)=O)C1C(O[Na])=O)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.