Total item
Cart Subtotal
$0.00 Biological Activity
AV-412 is an EGFR/HER2 inhibitor that binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 11.75 mL | 58.73 mL | 117.45 mL |
| 0.5 mM | 2.35 mL | 11.75 mL | 23.49 mL |
| 1 mM | 1.17 mL | 5.87 mL | 11.75 mL |
| 5 mM | 0.23 mL | 1.17 mL | 2.35 mL |
*The above data is based on the productmolecular weight 851.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11028 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 851.4 |
| Formula | C27H28ClFN6O.2C7H8O3S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 451493-31-5 |
| Synonyms | AV412, MP-412 |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CC(C)(C#CC1=CC2=C(C=C1NC(=O)C=C)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)N4CCN(CC4)C |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
ASP8273 (Naquotinib)
ASP8273 is an orally available, irreversible, third-generation, mutant-selective, epidermal growth factor receptor (EGFR) inhibitor, with po…
SU-5402
SU-5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor…
AG-1478 (Tyrphostin AG-1478)
AG-1478 (Tyrphostin AG-1478) is an inhibitor of EGFR kinase with an IC50 value of 3 nM.
WHI-P180
WHI-P180 is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.
AEE788
AEE788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor that inhibits phosphorylation of the tyrosine kinases of EGFR, …
Gefitinib (Iressa)
Gefitinib is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells.
Boceprevir (SCH-503034)
Boceprevir is a protease inhibitor used as a treatment for hepatitis C genotype 1.
AZD-9291 (Osimertinib)
AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cance…
Keywords:buy AV-412 | AV-412 Supplier | purchase AV-412 | AV-412 cost | AV-412 manufacturer | order AV-412 | AV-412 distributor | buy 451493-31-5| 451493-31-5 Supplier | purchase 451493-31-5 | 451493-31-5 cost | 451493-31-5 manufacturer | order 451493-31-5 | 451493-31-5 distributor
Adooq Quality Guarantee
We promise all products perform as described.