AV-412

Catalog No.: A11028

EGFR inhibitor

AV-412 Chemical Structure

CAS NO. 451493-31-5

AV-412 is an EGFR/HER2 inhibitor that binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis.

Availability: In stock

Package Price Qty
2 mg
$60.00
5 mg
$99.00
10 mg
$165.00
50 mg
$495.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AV-412 is an EGFR/HER2 inhibitor that binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.75 mL 58.73 mL 117.45 mL
0.5 mM 2.35 mL 11.75 mL 23.49 mL
1 mM 1.17 mL 5.87 mL 11.75 mL
5 mM 0.23 mL 1.17 mL 2.35 mL

*The above data is based on the productmolecular weight 851.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11028
Actions Inhibitor
M. Wt 851.4
Formula C27H28ClFN6O.2C7H8O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 451493-31-5
Synonyms AV412, MP-412
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CC(C)(C#CC1=CC2=C(C=C1NC(=O)C=C)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)N4CCN(CC4)C

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