Fig. 1 · Structure
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Avasopasem manganese
Superoxide Dismutase Mimetic
Avasopasem manganese is a potent superoxide dismutase mimetic that facilitates the conversion of superoxide anions (O2*- ) to hydrogen peroxide (H2O2). This mechanism helps in mitigating oxidative stress, which is significant in the pathophysiology of severe oral mucositis (SOM) and cancer. Avasopasem manganese serves as a valuable reagent for research focused on oxidative damage and therapeutic interventions in related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 435327-40-5 |
| Applications | Superoxide Dismutase Mimetic |
| Formula | C21H35Cl2MnN5 |
| Molecular Weight | 483.38 |
| Synonyms | GC-4419; M-40419 |
| SMILES | [Cl-][Mn+2]1234([N]5=C6C[NH]1[C@](CCCC7)([H])[C@@]7([H])[NH]2CC[NH]3[C@]8([H])[C@@](CCCC8)([H])[NH]4CC5=CC=C6)[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.