Fig. 1 · Structure
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AVE 0991 sodium salt
Ang-(1-7) Receptor Agonist
AVE 0991 sodium salt is a nonpeptide compound that acts as an agonist for the Ang-(1-7) receptor Mas. With an IC50 of 21 nM, it effectively competes for high-affinity binding of [125I]-Ang-(1-7) in bovine aortic endothelial cell membranes. This compound is instrumental in studying the Renin-Angiotensin System and its role in cardiovascular and metabolic research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 306288-04-0 |
| Applications | Ang-(1-7) Receptor Agonist |
| Formula | C29H31N4NaO5S2 |
| Molecular Weight | 602.70 |
| SMILES | O=S(C1=C(C2=CC=C(CN3C(C=O)=C(OC)N=C3C4=CC=CC=C4)C=C2)C=C(CC(C)C)S1)([N-]C(NCC)=O)=O.[Na+] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.