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AVE-5997

D3 Antagonist

AVE-5997 is a selective D3 dopamine receptor antagonist. It effectively reduces hyperactivity induced by MK-801, making it a valuable tool for studying dopaminergic dysregulation. This compound is particularly relevant in the research of schizophrenia and related neuropsychiatric disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	452917-21-4
Applications	D3 Antagonist
Formula	C₂₅H₂₉F₃N₄OS
Molecular Weight	490.58
SMILES	O=C(NCCCCN1CCN(C2=CSC3=CC(C(F)(F)F)=CC=C32)CC1)NC4=CC=C(C)C=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.