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AXC-879

Catalog No.: A35461
TLR Agonist
AXC-879 is a Toll-like receptor (TLR) agonist with an EC50 of 157.2 nM. This compound exhibits significant immunostimulatory activity, promoting innate immune responses. Additionally, AXC-879 serves as an antibody-drug conjugate (ADC) cytotoxin and is suitable for ADC synthesis, enabling targeted delivery of therapeutic agents in research applications.
AXC-879 2479277-22-8 TLR Agonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAXC-879 is a Toll-like receptor (TLR) agonist with an EC50 of 157.2 nM. This compound exhibits significant immunostimulatory activity, promoting innate immune responses. Additionally, AXC-879 serves as an antibody-drug conjugate (ADC) cytotoxin and is suitable for ADC synthesis, enabling targeted delivery of therapeutic agents in research applications.
Product Information
Catalog NumA35461
FormulaC26H38N8O4
Molecular Weight526.63
CAS Number2479277-22-8
SMILESO=C1NC2=C(N1CC3=CC=C(CN4CCC(CC4)CCNC(CON)=O)C=C3)N=C(OCCCC)N=C2N
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Immunology & Inflammation > Toll-like Receptors