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AXIN2/β-catenin-IN-1

Anticancer Agent

AXIN2/β-catenin-IN-1 is an inhibitor of the Wnt/β-catenin signaling pathway, targeting β-catenin activity to disrupt tumor cell behavior. This compound effectively impedes cellular invasion, migration, and colony formation in tumor cells, demonstrating significant anticancer properties. Additionally, AXIN2/β-catenin-IN-1 induces cell cycle arrest in EC-9706 and HT-29 cancer cell lines at the G2/M phase and inhibits overall cell proliferation. Its application is particularly relevant in gastrointestinal cancer research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3004884-16-3
Applications	Anticancer Agent
Formula	C₁₄H₈F₅NO₂S
Molecular Weight	349.28
SMILES	O=S(C1=C(C(F)=C(C(F)=C1F)F)F)(N2CC3=C(C2)C=CC=C3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.