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Axitinib

Catalog No.: A10103
VEGFR inhibitor
Adooq's Axitinib has been cited by 5 publications
Axitinib is a small molecule tyrosine kinase inhibitor,which inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117).
Axitinib 319460-85-0 VEGFR inhibitor
Grouped product items
Size Price Stock Qty
25mg
$25.00
In stock
50mg
$35.00
In stock
100mg
$55.00
In stock
250mg
$80.00
In stock
500mg
$145.00
In stock
1g
$210.00
In stock
10mM * 1mL in DMSO
$40.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Adooq's Axitinib has been cited by 5 publications
  • Sophie J. Bakri, .et al. , PLoS One, 2024, 19(6): e0304782 PMID: 38833447
  • Hongwan Ding, .et al. , Toxicol Appl Pharmacol, 2024, May:486:116950 PMID: 38701902
  • Hongwan Ding, .et al. , Research Square, 2023, Dec 28
  • Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138
  • Youcef M. Rustum, .et al. , Int J Mol Sci, 2018, Nov; 19(11): 3378 PMID: 30380599
Biological Activity
DescriptionAxitinib is a small molecule tyrosine kinase inhibitor,which inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117).
Targets
TargetValue
Cell Research
Cell LineTypeValueDescriptionReferences
Product Information
Catalog NumA10103
FormulaC22H18N4OS
Molecular Weight386.5
CAS Number319460-85-0
SMILESCNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)/C=C/C4=CC=CC=N4
SynonymsAG 013736
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSOWarmed: 30 mg/mL (77.62 mM)
WaterInsoluble
EthanolInsoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM25.87 mL129.37 mL258.73 mL
0.5 mM5.17 mL25.87 mL51.75 mL
1 mM2.59 mL12.94 mL25.87 mL
5 mM0.52 mL2.59 mL5.17 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

Protein Tyrosine Kinases > PDGFR
Protein Tyrosine Kinases > VEGFR
Protein Tyrosine Kinases > c-Kit
Angiogenesis > PDGFR
Angiogenesis > VEGFR