Axitinib

Name: Axitinib
SKU: A10103
Price: 32 USD
Rating: 5 (5 reviews)

Catalog No.: A10103

VEGFR inhibitor

Adooq's Axitinib has been cited by 5 publications

Axitinib is a small molecule tyrosine kinase inhibitor,which inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117).

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Grouped product items
Product Name	Price	Stock
Axitinib 50mg	Special Price $32.00 Regular Price $40.00	In stock
Axitinib 100mg	Special Price $56.00 Regular Price $70.00	In stock
Axitinib 250mg	Special Price $96.00 Regular Price $120.00	In stock
*Axitinib 10mM 1mL in DMSO**	Special Price $49.60 Regular Price $62.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's Axitinib has been cited by 5 publications

Sophie J. Bakri, .et al. , PLoS One, 2024, 19(6): e0304782 PMID: 38833447

Hongwan Ding, .et al. , Toxicol Appl Pharmacol, 2024, May:486:116950 PMID: 38701902

Hongwan Ding, .et al. , Research Square, 2023, Dec 28

Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138

Youcef M. Rustum, .et al. , Int J Mol Sci, 2018, Nov; 19(11): 3378 PMID: 30380599

Biological Activity

Discription

Axitinib is a small molecule tyrosine kinase inhibitor,which inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117).

Targets

Target	Value

Product Information

Catalog Num	A10103
Formula	C22H18N4OS
Molecular Weight	386.5
CAS Number	319460-85-0
SMILES	CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)/C=C/C4=CC=CC=N4
Synonyms	AG 013736
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	Warmed: 30 mg/mL (77.62 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.87 mL	129.37 mL	258.73 mL
0.5 mM	5.17 mL	25.87 mL	51.75 mL
1 mM	2.59 mL	12.94 mL	25.87 mL
5 mM	0.52 mL	2.59 mL	5.17 mL

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