AXL-IN-14 is a highly potent, orally bioavailable inhibitor of AXL, exhibiting an impressive IC50 value of 0.8 nM. This compound effectively disrupts Gas6/AXL-mediated cell migration and invasion while reducing the expression levels of phospho-AXL and phospho-AKT proteins. AXL-IN-14 demonstrates significant anti-tumor activity, making it a valuable tool for research in cancer therapeutics and metastasis studies.
AXL-IN-14 is a highly potent, orally bioavailable inhibitor of AXL, exhibiting an impressive IC50 value of 0.8 nM. This compound effectively disrupts Gas6/AXL-mediated cell migration and invasion while reducing the expression levels of phospho-AXL and phospho-AKT proteins. AXL-IN-14 demonstrates significant anti-tumor activity, making it a valuable tool for research in cancer therapeutics and metastasis studies.
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