AYK004

Catalog No.: A35508
TLR7/8 Agonist
AYK004 is a TLR7/8 agonist that stimulates immune responses through the activation of the Toll-like receptor signaling pathway. As an adenine derivative with an optimized hydrophilic-lipophilic balance, AYK004 enhances loading capacity and stability in immunoadjuvant systems, such as liposomes. This compound is particularly useful for research applications focused on innate immunity and the development of vaccine adjuvants, while minimizing potential side effects associated with systemic immunity.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAYK004 is a TLR7/8 agonist that stimulates immune responses through the activation of the Toll-like receptor signaling pathway. As an adenine derivative with an optimized hydrophilic-lipophilic balance, AYK004 enhances loading capacity and stability in immunoadjuvant systems, such as liposomes. This compound is particularly useful for research applications focused on innate immunity and the development of vaccine adjuvants, while minimizing potential side effects associated with systemic immunity.
Product Information
Catalog NumA35508
FormulaC17H26F3N7O2
Molecular Weight417.43
CAS Number3031612-90-2
SMILESO=C1NC2=C(N1CCCCCN3CCNCC3)N=C(OC(C(F)(F)F)C)N=C2N
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