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AZ 23

TrkA inhibitor

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Catalog No. A12666

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AZ 23 5mg A12666-5
AZ 23 10mg A12666-10
AZ 23 25mg A12666-25
AZ 23 50mg A12666-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AZ 23 is a potent and selective tyrosine kinase Trk inhibitor with IC50 to 2 and 8 nM for TrkA and TrkB respectively

AZ 23

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Chemical Information

Catalog Num A12666
Actions Inhibitor
M. Wt 391.83
Formula C17H19ClFN7O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 915720-21-7
Synonyms AZ23, AZ-23
SMILES C[[email protected]@H](C1=NC=C(C=C1)F)NC2=NC=C(C(=N2)NC3=CC(=NN3)OC(C)C)Cl

Biological Activity

AZ 23 is a potent and selective tyrosine kinase Trk inhibitor with IC50 to 2 and 8 nM for TrkA and TrkB respectively

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.52 mL 127.61 mL 255.21mL
0.5 mM 5.1 mL 25.52 mL 51.04 mL
1 mM 2.55 mL 12.76 mL 25.52 mL
5 mM 0.51 mL 2.55 mL 5.1 mL

*The above data is based on the productmolecular weight 391.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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