AZ 23

Catalog No.: A12666

TrkA inhibitor

AZ 23

AZ 23 Chemical Structure

CAS NO. 915720-21-7

AZ 23 is a potent and selective tyrosine kinase Trk inhibitor with IC50 to 2 and 8 nM for TrkA and TrkB respectively

Availability: In stock

Package Price Qty
5 mg
$145.00
10 mg
$235.00
25 mg
$505.00
50 mg
$865.00
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Biological Activity

AZ 23 is a potent and selective tyrosine kinase Trk inhibitor with IC50 to 2 and 8 nM for TrkA and TrkB respectively
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.52 mL 127.61 mL 255.21 mL
0.5 mM 5.1 mL 25.52 mL 51.04 mL
1 mM 2.55 mL 12.76 mL 25.52 mL
5 mM 0.51 mL 2.55 mL 5.1 mL

*The above data is based on the productmolecular weight 391.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12666
Actions Inhibitor
CAS No. 915720-21-7
Formula C17H19ClFN7O
M. Wt 391.83
Solubility DMSO
Purity >98%
Synonyms AZ23, AZ-23
SMILES C[[email protected]@H](C1=NC=C(C=C1)F)NC2=NC=C(C(=N2)NC3=CC(=NN3)OC(C)C)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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