Fig. 1 · Structure
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AZ'9567
MAT2A Inhibitor
AZ'9567 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A), which plays a critical role in cellular metabolism and proliferation. This compound demonstrates significant antiproliferative effects against MTAP knockout HCT116 cells, with a pIC50 value of 8.9. AZ'9567 is a valuable tool for investigating the role of MAT2A in cancer biology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3056570-19-2 |
| Applications | MAT2A Inhibitor |
| Formula | C24H19F2N5O2 |
| Molecular Weight | 447.44 |
| SMILES | O=C1C(C2=CC3=CN(C)N=C3C=C2)=CC(NN=C4C5CC5)=C4N1C6=CC=C(OC(F)F)C=C6 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.