Fig. 1 · Structure
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AZ-TAK1
TAK1 Inhibitor
AZ-TAK1 is an ATP-competitive small molecule inhibitor targeting TAK1, a crucial kinase in inflammatory and stress response pathways. By inhibiting TAK1, AZ-TAK1 effectively dephosphorylates downstream signaling proteins, including p38 and IκB-α. This compound is valuable for research applications focused on cancer biology, inflammation, and cellular stress responses in lymphoma and other cell line studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1413440-36-4 |
| Applications | TAK1 Inhibitor |
| Formula | C25H28FN7O2 |
| Molecular Weight | 477.53 |
| SMILES | FC1=C(C2=CN=C3C=CC=NN32)N=C(NC4=CC(OCCN5CCC(CC5)O)=CC(CC)=C4)N=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.