Fig. 1 · Structure

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AZ12559322

mGluR Modulator

AZ12559322 is a positive allosteric modulator of the metabotropic glutamate receptor 2 (mGluR2), exhibiting a Ki value of 1.31 nM. This compound enhances receptor signaling and has applications in neurological research, particularly in studying conditions related to synaptic transmission and excitatory neurotransmission modulations. Its potent activity makes it a valuable tool for investigating mGluR2 functions and potential therapeutic outcomes in neuropsychiatric disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 947184-66-9
Applications mGluR Modulator
Formula C19H22N2O3S
Molecular Weight 358.45
SMILES
CC(C=C1C2=CC(NS(C)(=O)=O)=CC=C2)=C3C(N(CC3=C1)C(C)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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