Fig. 1 · Structure
Documents & Downloads
AZ7550-d5
Labeled AZ7550
AZ7550-d5 is a deuterium-labeled variant of AZ7550, a selective inhibitor targeting the insulin-like growth factor 1 receptor (IGF1R). This compound exhibits significant biological activity, with an IC50 value of 1.6 μM, making it a valuable tool for studying IGF1R signaling pathways. It is useful in research applications related to cancer biology and therapeutic development, particularly in the context of Osimertinib (AZD9291) metabolism and efficacy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2719690-99-8 |
| Applications | Labeled AZ7550 |
| Formula | C27H26D5N7O2 |
| Molecular Weight | 490.61 |
| SMILES | O=C(NC1=CC(NC2=NC=CC(C3=CN(C([2H])([2H])[2H])C4=C3C=CC=C4)=N2)=C(OC)C=C1N(C)CCNC)/C=C([2H])\[2H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.