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Biological Activity
AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor, with a Ki of 43 nM and an IC50 of 300 nM for KIFC1.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.84 mL | 89.19 mL | 178.37 mL |
| 0.5 mM | 3.57 mL | 17.84 mL | 35.67 mL |
| 1 mM | 1.78 mL | 8.92 mL | 17.84 mL |
| 5 mM | 0.36 mL | 1.78 mL | 3.57 mL |
*The above data is based on the productmolecular weight 560.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21400 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1449578-65-7 |
| Formula | C28H31F3N4O3S |
| M. Wt | 560.63 |
| Purity | >98% |
| Synonyms | AZ 82, AZ-82 |
| SMILES | O=C(C1=CC(CCC)=C(C)S1)N[C@H](CC2=CC=C(C3=CC=CC(OC(F)(F)F)=C3)N=C2)C(N[C@H]4CNCC4)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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