Fig. 1 · Structure

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Azasetron

5-HT Receptor

Azasetron, a 5-HT3 receptor antagonist, is an effective antiemetic agent. It is primarily utilized to prevent postoperative nausea and vomiting as well as nausea induced by chemotherapy. Importantly, Azasetron does not interfere with neutrophil chemotaxis or phagocytosis, nor does it scavenge superoxide anions or hydrogen peroxide produced by cell-free systems, making it a valuable tool in various research applications related to antiemetic efficacy.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 123040-69-7
Applications 5-HT Receptor
Formula C17H20ClN3O3
Molecular Weight 349.81
Synonyms (Rac)-SENS-401 free base
SMILES
O=C(C1=CC(Cl)=CC2=C1OCC(N2C)=O)NC3CN4CCC3CC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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