AZD-2066 hydrochloride is a selective antagonist of the metabotropic glutamate receptor 5 (mGluR5) with the ability to penetrate the blood-brain barrier. This compound activates the brain-derived neurotrophic factor (BDNF) and trkB signaling pathway, making it relevant for research into neuropathic pain, major depressive disorder, and gastroesophageal reflux disease. AZD-2066 hydrochloride serves as a valuable tool for investigating the therapeutic potential of mGluR5 modulation in these conditions.
AZD-2066 hydrochloride is a selective antagonist of the metabotropic glutamate receptor 5 (mGluR5) with the ability to penetrate the blood-brain barrier. This compound activates the brain-derived neurotrophic factor (BDNF) and trkB signaling pathway, making it relevant for research into neuropathic pain, major depressive disorder, and gastroesophageal reflux disease. AZD-2066 hydrochloride serves as a valuable tool for investigating the therapeutic potential of mGluR5 modulation in these conditions.
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