AZD-3965

Catalog No.: A14186

MCT1 inhibitor

AZD-3965

AZD-3965 Chemical Structure

CAS NO. 1448671-31-5

AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, is 6 fold selective over MCT2 and does not inhibit MCT4 at 10 μM.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$150.00
25 mg
$260.00
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Biological Activity

AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, is 6 fold selective over MCT2 and does not inhibit MCT4 at 10 μM.
Targets
MCT1
In vitro DMSO 96 mg/mL (186.22 mM)
Water Insoluble
Ethanol 96 mg/mL (186.22 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.4 mL 96.99 mL 193.99 mL
0.5 mM 3.88 mL 19.4 mL 38.8 mL
1 mM 1.94 mL 9.7 mL 19.4 mL
5 mM 0.39 mL 1.94 mL 3.88 mL

*The above data is based on the productmolecular weight 515.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14186
Actions Inhibitor
CAS No. 1448671-31-5
Formula C21H24F3N5O5S
M. Wt 515.5
Solubility DMSO
Purity >98%
Synonyms AZD3965,AZD 3965
SMILES O=C1N(C(C)C)C2=C(C(C(N3OC[[email protected]@](C)(O)C3)=O)=C(CC4=C(C(F)(F)F)NN=C4C)S2)C(N1C)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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