Biological Activity
AZD-4635 (HTL1071) is an oral A2AR antagonist that binds to human A2AR with a Ki of 1.7 nM and with > 30-fold selectivity over other adenosine receptors.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 31.67 mL | 158.36 mL | 316.73 mL |
0.5 mM | 6.33 mL | 31.67 mL | 63.35 mL |
1 mM | 3.17 mL | 15.84 mL | 31.67 mL |
5 mM | 0.63 mL | 3.17 mL | 6.33 mL |
*The above data is based on the productmolecular weight 315.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16820 |
---|---|
Actions | Antagonist |
M. Wt | 315.73 |
Formula | C15H11ClFN5 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1321514-06-0 |
Synonyms | AZD4635, AZD 4635, HTL-1071, HTL 1071 |
SMILES | NC1=NC(C2=CC=C(F)C=C2)=C(C3=CC(C)=NC(Cl)=C3)N=N1 |
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