AZD-8529 mesylate is a potent and highly selective positive allosteric modulator (PAM) of the metabotropic glutamate receptor 2 (mGluR2), exhibiting an EC50 of 285 nM. It demonstrates no significant allosteric modulation at concentrations up to 25 µM for mGluR subtypes 1, 3, 4, 5, 6, 7, and 8. This compound is instrumental for research on neurological disorders and mGluR2-related signaling pathways.
AZD-8529 mesylate is a potent and highly selective positive allosteric modulator (PAM) of the metabotropic glutamate receptor 2 (mGluR2), exhibiting an EC50 of 285 nM. It demonstrates no significant allosteric modulation at concentrations up to 25 µM for mGluR subtypes 1, 3, 4, 5, 6, 7, and 8. This compound is instrumental for research on neurological disorders and mGluR2-related signaling pathways.
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