Fig. 1 · Structure
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AZD-9819
Neutrophil Elastase Inhibitor
AZD-9819 is a potent inhibitor of neutrophil elastase, an enzyme implicated in the pathogenesis of various inflammatory diseases. Its effective inhibition of HNE makes it a valuable tool in the study of chronic obstructive pulmonary disease (COPD) and related pulmonary conditions. Researchers can utilize AZD-9819 to explore the therapeutic potential of targeting neutrophil elastase in mitigating inflammation and tissue damage within the lungs.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 956907-23-6 |
| Applications | Neutrophil Elastase Inhibitor |
| Formula | C25H19F3N6O2 |
| Molecular Weight | 492.45 |
| SMILES | O=C(C1=NC(C2=CC=NN2C3=CC=C(C#N)C=C3)=C(C)N(C4=CC=CC(C(F)(F)F)=C4)C1=O)NCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.