Fig. 1 · Structure
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AZD-CO-Ph-PEG4-Ph-CO-AZD
Linker for Antibody-siRNA Conjugate
AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker designed for the synthesis of antibody-siRNA conjugates. This compound facilitates the covalent attachment of small interfering RNA (siRNA) to antibodies, enhancing targeted delivery and therapeutic efficacy. It serves as a valuable tool in the development of targeted RNAi therapies and studies involving gene silencing mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2569143-72-0 |
| Applications | Linker for Antibody-siRNA Conjugate |
| Formula | C26H28N2O8 |
| Molecular Weight | 496.51 |
| SMILES | O=C(N1C(CC1)=O)C2=CC=C(C=C2)OCCOCCOCCOC3=CC=C(C(N4C(CC4)=O)=O)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.