Fig. 1 · Structure
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AZD1092
GK Activator
AZD1092 is an orally active glucokinase (GK) activator with an EC50 value of 0.03 μM. It enhances glycolysis and insulin secretion, making it a valuable tool in the study of Type 2 Diabetes (T2D) and related metabolic disorders. Its role in modulating blood glucose levels positions AZD1092 as a critical compound for advancing research in diabetes treatment and management.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 871656-65-4 |
| Applications | GK Activator |
| Formula | C24H26N4O5 |
| Molecular Weight | 450.49 |
| SMILES | O=C(C1=CC(O[C@H](CO)C)=CC(OC2=CC=C(C=C2)C(N3CCC3)=O)=C1)NC4=NN(C=C4)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.