AZD2858

Catalog No.: A13060

GSK-3β inhibitor

AZD2858

AZD2858 Chemical Structure

CAS NO. 486424-20-8

AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, activating Wnt signaling, increases bone mass in rats.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $80.00

Special Price $72.00

25 mg

Regular Price: $160.00

Special Price $144.00

50 mg

Regular Price: $280.00

Special Price $252.00

100 mg

Regular Price: $500.00

Special Price $450.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, activating Wnt signaling, increases bone mass in rats.
Targets
GSK-3
68 nM
In vitro (25°C) DMSO 7 mg/mL (15.43 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.05 mL 110.25 mL 220.5 mL
0.5 mM 4.41 mL 22.05 mL 44.1 mL
1 mM 2.2 mL 11.02 mL 22.05 mL
5 mM 0.44 mL 2.2 mL 4.41 mL

*The above data is based on the productmolecular weight 453.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13060
Actions Inhibitor
M. Wt 453.52
Formula C21H23N7O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 486424-20-8
Synonyms AZD-2858, AZD 2858
SMILES CN1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C3=CN=C(C(=N3)C(=O)NC4=CN=CC=C4)N

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