Fig. 1 · Structure

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AZD5213

H3 Receptor Antagonist

AZD5213 is a selective and competitive antagonist of the human H3 receptor, exhibiting a pKi value of 9.3 for hH3R. This compound is instrumental in researching the modulation of sleep and cognitive functions, making it valuable for studies investigating the role of histamine signaling in neurobiological processes. Its specificity and potency enable detailed exploration of H3 receptor-related pathways in various experimental contexts.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 1119807-02-1
Applications H3 Receptor Antagonist
Formula C19H25N3O2
Molecular Weight 327.42
SMILES
O=C(N)C1=CC=C([C@@H]2[C@@H](C(N3CCN(C4CCC4)CC3)=O)C2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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