AZD8233 is an antisense oligonucleotide (ASO) that targets proprotein convertase subtilisin/kexin type 9 (PCSK9) to inhibit its protein synthesis. By reducing levels of PCSK9, AZD8233 enhances the availability of LDL receptors, which facilitates the clearance of low-density lipoprotein (LDL) from circulation and contributes to lowering LDL cholesterol (LDL-C) levels. This compound is applicable in research focused on lipid metabolism and cardiovascular disease.
AZD8233 is an antisense oligonucleotide (ASO) that targets proprotein convertase subtilisin/kexin type 9 (PCSK9) to inhibit its protein synthesis. By reducing levels of PCSK9, AZD8233 enhances the availability of LDL receptors, which facilitates the clearance of low-density lipoprotein (LDL) from circulation and contributes to lowering LDL cholesterol (LDL-C) levels. This compound is applicable in research focused on lipid metabolism and cardiovascular disease.
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