AZD8329

Catalog No.: A21081

11β-HSD1 inhibitor

AZD8329

AZD8329 Chemical Structure

CAS NO. 1048668-70-7

AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3.

Availability: In stock

Package Price Qty
5 mg
$225.00
10 mg
$388.00
50 mg
$1,150.00
100 mg
$2,300.00
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Biological Activity

AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.72 mL 118.62 mL 237.23 mL
0.5 mM 4.74 mL 23.72 mL 47.45 mL
1 mM 2.37 mL 11.86 mL 23.72 mL
5 mM 0.47 mL 2.37 mL 4.74 mL

*The above data is based on the productmolecular weight 421.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21081
Actions Inhibitor
M. Wt 421.53
Formula C25H31N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1048668-70-7
Synonyms AZD 8329, AZD-8329
SMILES O=C(O)C1=CC=C(N2N=CC(C(NC3C(C4)CC5CC4CC3C5)=O)=C2C(C)(C)C)C=C1

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