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AZD8797 is an allosteric non-competitive and orally active modulator of the human CX3CR1 receptor; antagonizes CX3CR1 and CXCR2 with Kis of 3.9 and 2800 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.78 mL | 123.9 mL | 247.79 mL |
| 0.5 mM | 4.96 mL | 24.78 mL | 49.56 mL |
| 1 mM | 2.48 mL | 12.39 mL | 24.78 mL |
| 5 mM | 0.5 mL | 2.48 mL | 4.96 mL |
*The above data is based on the productmolecular weight 403.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21230 |
|---|---|
| Actions | Modulator |
| CAS No. | 911715-90-7 |
| Formula | C19H25N5OS2 |
| M. Wt | 403.56 |
| Purity | >98% |
| SMILES | CC(C)C[[email protected]@H](NC1=NC(S[[email protected]@H](C)C2=CC=CC=C2)=NC3=C1SC(N)=N3)CO |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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