Fig. 1 · Structure

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AZD9496 deacrylic acid phenol

Ligand for Target Protein for PROTAC

AZD9496 deacrylic acid phenol is a ligand targeting specific protein associated with PROTAC (Proteolysis Targeting Chimeras) technology. This compound plays a critical role in the design of selective ER (estrogen receptor) degraders, facilitating targeted protein degradation. Its use in research applications allows for the exploration of novel therapeutic strategies in cancer and other estrogen-related diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2173404-70-9
Applications Ligand for Target Protein for PROTAC
Formula C22H23F3N2O
Molecular Weight 388.43
SMILES
CC(C)(F)CN1[C@@](C2=C(C=C(C=C2F)O)F)([H])C3=C(C[C@H]1C)C4=CC=CC=C4N3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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