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Azelastine is a potent, second-generation, selective, histamine antagonist (histamine-H1-receptor antagonist).
Targets
| Histamine receptor | ||||
| In vitro | DMSO | 84 mg/mL (200.78 mM) | |
| Water | 35 mg/mL (83.66 mM) | ||
| Ethanol | 84 mg/mL (200.78 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.9 mL | 119.5 mL | 239.01 mL |
| 0.5 mM | 4.78 mL | 23.9 mL | 47.8 mL |
| 1 mM | 2.39 mL | 11.95 mL | 23.9 mL |
| 5 mM | 0.48 mL | 2.39 mL | 4.78 mL |
*The above data is based on the productmolecular weight 418.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A10117 |
|---|---|
| Actions | N/A |
| M. Wt | 418.4 |
| Formula | C22H24ClN3O.HCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 79307-93-0 |
| Synonyms | Allergodil,Rhinolast, Astelin, Optilas, Optivar |
| SMILES | CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.Cl |
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