Fig. 1 · Structure
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Azetirelin
Biochemical Reagent
Azetirelin is a synthetic analogue of thyrotropin-releasing hormone (TRH) that primarily targets TRH receptors. It exhibits biological activity by modulating the release of thyroid-stimulating hormone (TSH) and prolactin. This compound is utilized in biochemical research to study the regulatory mechanisms of the hypothalamic-pituitary-thyroid axis and to explore potential therapeutic applications in thyroid disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 95729-65-0 |
| Applications | Biochemical Reagent |
| Formula | C15H20N6O4 |
| Molecular Weight | 348.36 |
| Synonyms | YM-14673 |
| SMILES | O=C([C@@H]1CC(N1)=O)N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(N)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.