Azintuxizumab vedotin

Azintuxizumab vedotin (ABBV-838) is an antibody-drug conjugate (ADC) specifically designed to target a unique epitope of CD2 subset 1, a cell-surface glycoprotein prevalently expressed on multiple myeloma cells. This targeted approach allows for the direct delivery of cytotoxic agents to the cancer cells, potentially enhancing therapeutic efficacy while minimizing off-target effects. Azintuxizumab vedotin is primarily utilized in research focused on the treatment and understanding of multiple myeloma.

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Biological Activity

Target & Activity

CD2 subset 1

Product Details

Manufacturer Adooq Bioscience
CAS Number 1826819-58-2
Synonyms ABBV-838

Storage

Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Customer Questions
Biosimilar antibodies are research-grade recombinant antibodies designed to closely resemble approved therapeutic antibodies in terms of amino acid sequence, structural characteristics, and biological activity. These antibodies are generated using recombinant expression technologies and retain the same variable regions as their corresponding reference therapeutics, thereby preserving target specificity and binding affinity. Owing to these properties, biosimilar antibodies serve as reliable and cost-effective research reagents for applications in drug discovery, pharmacological studies, and basic biomedical research. Research-grade biosimilar antibodies have been successfully expressed and functionally validated against a wide range of widely studied targets. These antibodies can be directly utilized as positive control reagents in drug discovery programs, as well as reference tools for rapid verification of the biological functions of target proteins in biochemical and cellular assays.
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