Fig. 1 · Structure
Documents & Downloads
Azt-pmap
NRTI Inhibitor
Azt-pmap is a nucleoside reverse transcriptase inhibitor (NRTI) that functions as an aryl phosphate derivative of AZT, demonstrating significant anti-HIV activity. This compound serves as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Azt-pmap is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds, making it valuable for diverse research applications in chemical biology and drug development.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 142629-81-0 |
| Applications | NRTI Inhibitor |
| Formula | C20H25N6O8P |
| Molecular Weight | 508.42 |
| SMILES | O=C(NC1=O)N(C=C1C)[C@@H]2O[C@H](COP(OC3=CC=CC=C3)(N[C@@H](C)C(OC)=O)=O)[C@@H](N=[N+]=[N-])C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.