Fig. 1 · Structure
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AZT triphosphate tetraammonium
Antiretroviral Agent
AZT triphosphate tetraammonium is an active triphosphate metabolite of the antiretroviral agent Zidovudine (AZT). This compound demonstrates significant antiretroviral activity by inhibiting HIV replication and is also effective against hepatitis B virus (HBV) DNA polymerase. Additionally, AZT triphosphate tetraammonium can activate the mitochondria-mediated apoptosis pathway, making it a valuable reagent for research into viral infections and apoptotic mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 106060-92-8 |
| Applications | Antiretroviral Agent |
| Formula | C10H28N9O13P3 |
| Molecular Weight | 575.30 |
| Synonyms | 3'-Azido-3'-deoxythymidine-5'-triphosphate tetraammonium |
| SMILES | O=C1NC(N([C@@H](C[C@@H]2N=[N+]=[N-])O[C@@H]2COP(OP(O)(OP(O)(O)=O)=O)(O)=O)C=C1C)=O.N.N.N.N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.