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B-Raf inhibitor 1 dihydrochloride is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.12 mL | 90.6 mL | 181.21 mL |
| 0.5 mM | 3.62 mL | 18.12 mL | 36.24 mL |
| 1 mM | 1.81 mL | 9.06 mL | 18.12 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.62 mL |
*The above data is based on the productmolecular weight 551.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21834 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 551.86 |
| Formula | C26H21Cl3N8 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1191385-19-9 |
| SMILES | CC1=CC=C2C(C=CN=C2NC3=CC=C(Cl)C=C3)=C1NC4=NC=CC=C4C5=NC=NC6=C5N=CN6.[H]Cl.[H]Cl |
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