B-Raf inhibitor 1 dihydrochloride

Catalog No.: A21834

Raf kinase inhibitor

B-Raf inhibitor 1 dihydrochloride

B-Raf inhibitor 1 dihydrochloride Chemical Structure

CAS NO. 1191385-19-9

B-Raf inhibitor 1 dihydrochloride is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

B-Raf inhibitor 1 dihydrochloride is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively.
In vitro DMSO 96 mg/mL (173.95 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.12 mL 90.6 mL 181.21 mL
0.5 mM 3.62 mL 18.12 mL 36.24 mL
1 mM 1.81 mL 9.06 mL 18.12 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 551.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21834
Actions Inhibitor
CAS No. 1191385-19-9
Formula C26H21Cl3N8
M. Wt 551.86
Purity >98%
SMILES CC1=CC=C2C(C=CN=C2NC3=CC=C(Cl)C=C3)=C1NC4=NC=CC=C4C5=NC=NC6=C5N=CN6.[H]Cl.[H]Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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