B-Raf inhibitor 1 dihydrochloride

Catalog No.: A21834

Raf kinase inhibitor

B-Raf inhibitor 1 dihydrochloride

B-Raf inhibitor 1 dihydrochloride Chemical Structure

CAS NO. 1191385-19-9

B-Raf inhibitor 1 dihydrochloride is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

B-Raf inhibitor 1 dihydrochloride is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.12 mL 90.6 mL 181.21 mL
0.5 mM 3.62 mL 18.12 mL 36.24 mL
1 mM 1.81 mL 9.06 mL 18.12 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 551.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21834
Actions Inhibitor
M. Wt 551.86
Formula C26H21Cl3N8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1191385-19-9
SMILES CC1=CC=C2C(C=CN=C2NC3=CC=C(Cl)C=C3)=C1NC4=NC=CC=C4C5=NC=NC6=C5N=CN6.[H]Cl.[H]Cl

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