B-Raf-inhibitor 1

Catalog No.: A14122

B-Raf inhibitor

B-Raf-inhibitor 1

B-Raf-inhibitor 1 Chemical Structure

CAS NO. 1093100-40-3

B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively

Availability: In stock

Package Price Qty
10 mg

Regular Price: $120.00

Special Price $108.00

25 mg

Regular Price: $250.00

Special Price $225.00

50 mg

Regular Price: $400.00

Special Price $360.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.88 mL 104.4 mL 208.79 mL
0.5 mM 4.18 mL 20.88 mL 41.76 mL
1 mM 2.09 mL 10.44 mL 20.88 mL
5 mM 0.42 mL 2.09 mL 4.18 mL

*The above data is based on the productmolecular weight 478.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A14122
Actions Inhibitor
M. Wt 478.94
Formula C26H19ClN8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1093100-40-3
Synonyms B-Raf inhibitor1, B-Raf inhibitor-1
SMILES CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC=C(C=C3)Cl)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6

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