Baclofen

Catalog No.: A18248

GABA agonist

Baclofen

Baclofen Chemical Structure

CAS NO. 1134-47-0

Baclofen is a GABA agonist specific for GABA-B receptors. Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing It acts at spinal and supraspinal sites, reducing excitatory transmission.

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500 mg
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Biological Activity

Baclofen is a GABA agonist specific for GABA-B receptors. Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing It acts at spinal and supraspinal sites, reducing excitatory transmission.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 46.8 mL 234.02 mL 468.03 mL
0.5 mM 9.36 mL 46.8 mL 93.61 mL
1 mM 4.68 mL 23.4 mL 46.8 mL
5 mM 0.94 mL 4.68 mL 9.36 mL

*The above data is based on the productmolecular weight 213.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18248
Actions Agonist
M. Wt 213.66
Formula C10H12ClNO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1134-47-0
Synonyms Baclofen; Lioresal, Liofen, Gablofen; Baclon; Kemstro
SMILES O=C(O)CC(C1=CC=C(Cl)C=C1)CN

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