Fig. 1 · Structure
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Baloxavir-d4
Stable Isotope
Baloxavir-d4 is a deuterium-labeled derivative of Baloxavir, specifically designed as a stable isotope. It functions as a potent and selective inhibitor of cap-dependent endonuclease (CEN) within the polymerase PA subunit of influenza A and B viruses. Baloxavir-d4 effectively inhibits viral RNA transcription and replication, demonstrating significant antiviral activity. This reagent is valuable for research applications focused on understanding the mechanisms of influenza virus infection and for the development of antiviral therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2415027-80-2 |
| Applications | Stable Isotope |
| Formula | C24H15D4F2N3O4S |
| Molecular Weight | 487.51 |
| Synonyms | Baloxavir acid-d4; S-033447-d4 |
| SMILES | FC1=C(C(CSC2=C3C=CC=C2)=C([C@@H]3N4[C@]5(N(C(C6=C(C(C=CN64)=O)O)=O)C([2H])(C([2H])(OC5)[2H])[2H])[H])C=C1)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.