Target & Activity
| Target | Activity | Value |
|---|---|---|
| CXCR4 |
Cellular Effect
| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| MCF7 | IC50 | 7.52 μM | Antitumor activity against human MCF7 cells assessed as cell viability incubated for 48 hrs by CCK8 assay | [PMID: 36753987] |
| NCI/ADR-RES | IC50 | > 100 μM | Cytotoxicity against human MCF7/ADR cells after 72 hrs by MTT assay | [PMID: 19523827] |
| Sf9 | IC50 | 1.7 μM | Inhibition of recombinant human PDE5A1 catalytic domain (535 to 860 residues) expressed in baculovirus infected sf9 cells using [3H]cGMP as substrate incubated for 15 mins by liquid scintillation counting method | [PMID: 26908025] |