Fig. 1 · Structure

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Baohuoside I

Cat. No. A14765 CAS 113558-15-9
Baohuoside I is an effective anti-cancer drug currently used for a variety of cancers in vitro.

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Biological Activity

Target & Activity

Target Activity Value
CXCR4  

Cellular Effect

Cell Line Activity Value Description Reference
MCF7 IC50 7.52 μM Antitumor activity against human MCF7 cells assessed as cell viability incubated for 48 hrs by CCK8 assay [PMID: 36753987]
NCI/ADR-RES IC50 > 100 μM Cytotoxicity against human MCF7/ADR cells after 72 hrs by MTT assay [PMID: 19523827]
Sf9 IC50 1.7 μM Inhibition of recombinant human PDE5A1 catalytic domain (535 to 860 residues) expressed in baculovirus infected sf9 cells using [3H]cGMP as substrate incubated for 15 mins by liquid scintillation counting method [PMID: 26908025]

Specifications

Manufacturer Adooq Bioscience
CAS Number 113558-15-9
Formula C27H30O10
Molecular Weight 514.52
Synonyms Icariin II; Icariside II
SMILES
CC1C(C(C(C(O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O)O)C4=CC=C(C=C4)OC)O)O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

SolventReported Solubility
DMSO 91 mg/mL (176.86 mM)

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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