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BAR-072

T4SS Inhibitor

BAR-072 is a small-molecule inhibitor that targets TraE, exhibiting a dissociation constant (KD) of 2.7 µM. It effectively inhibits the horizontal transfer of the antibiotic resistance-associated plasmid pKM101. As a candidate compound, BAR-072 shows potential for blocking the dissemination of bacterial resistance genes, making it an important tool for research in infectious disease and antimicrobial resistance management.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2068867-65-0
Applications	T4SS Inhibitor
Formula	C₁₈H₁₃N₃O₆
Molecular Weight	367.31
SMILES	O=C(C1=C(C=CC(O)=C1)O)N/N=C/C2=CC=C(O2)C3=CC=CC=C3[N+]([O-])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.